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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRAF
All Species:
21.82
Human Site:
S151
Identified Species:
34.29
UniProt:
P15056
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15056
NP_004324.2
766
84437
S151
V
A
R
S
N
P
K
S
P
Q
K
P
I
V
R
Chimpanzee
Pan troglodytes
XP_001155024
767
84561
S151
V
A
R
S
N
P
K
S
P
Q
K
P
I
V
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532749
767
85780
V128
L
P
N
K
Q
R
T
V
V
P
A
R
C
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P28028
804
88899
S135
A
S
R
N
N
P
K
S
P
Q
K
P
I
V
R
Rat
Rattus norvegicus
P11345
648
72910
L78
N
V
R
N
G
M
S
L
H
D
C
L
M
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516512
799
90020
S131
A
A
R
G
N
P
K
S
P
Q
K
P
I
V
R
Chicken
Gallus gallus
Q04982
806
89347
S151
M
S
R
N
N
P
K
S
P
Q
K
P
I
V
R
Frog
Xenopus laevis
P09560
638
71941
T68
Y
L
P
N
K
Q
R
T
V
V
N
V
R
S
G
Zebra Danio
Brachydanio rerio
NP_991307
777
86403
S161
A
T
R
G
N
P
R
S
P
Q
K
P
I
V
R
Tiger Blowfish
Takifugu rubipres
NP_001032957
778
86510
V157
T
P
T
D
G
S
R
V
N
P
R
S
P
Q
K
Fruit Fly
Dros. melanogaster
P11346
782
88616
G168
N
D
L
T
D
S
L
G
S
Q
P
G
S
Q
C
Honey Bee
Apis mellifera
XP_396892
715
80060
V135
Q
Q
R
T
S
V
Q
V
R
E
G
L
S
L
R
Nematode Worm
Caenorhab. elegans
Q07292
813
90389
V158
L
P
G
N
E
L
W
V
H
S
E
Y
L
N
T
Sea Urchin
Strong. purpuratus
XP_781094
750
85072
H142
R
E
F
T
N
Q
Q
H
P
K
S
P
L
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
A183
A
L
R
L
S
S
E
A
T
C
A
D
D
P
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
92.9
N.A.
88.8
50.2
N.A.
85.7
89.8
49.3
83.5
82.9
42.8
50.6
30.7
49.3
Protein Similarity:
100
99.3
N.A.
93.4
N.A.
89.3
62.2
N.A.
86.7
90.9
61.3
87.5
87.1
57.9
65
46.6
62.6
P-Site Identity:
100
100
N.A.
0
N.A.
80
6.6
N.A.
86.6
80
0
73.3
0
6.6
13.3
0
20
P-Site Similarity:
100
100
N.A.
6.6
N.A.
93.3
20
N.A.
86.6
100
20
80
20
20
46.6
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
20
0
0
0
0
0
7
0
0
14
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
7
0
7
0
7
% C
% Asp:
0
7
0
7
7
0
0
0
0
7
0
7
7
0
0
% D
% Glu:
0
7
0
0
7
0
7
0
0
7
7
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
14
14
0
0
7
0
0
7
7
0
7
7
% G
% His:
0
0
0
0
0
0
0
7
14
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% I
% Lys:
0
0
0
7
7
0
34
0
0
7
40
0
0
7
7
% K
% Leu:
14
14
7
7
0
7
7
7
0
0
0
14
14
7
0
% L
% Met:
7
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% M
% Asn:
14
0
7
34
47
0
0
0
7
0
7
0
0
7
7
% N
% Pro:
0
20
7
0
0
40
0
0
47
14
7
47
7
7
0
% P
% Gln:
7
7
0
0
7
14
14
0
0
47
0
0
0
14
7
% Q
% Arg:
7
0
60
0
0
7
20
0
7
0
7
7
7
0
47
% R
% Ser:
0
14
0
14
14
20
7
40
7
7
7
7
14
14
0
% S
% Thr:
7
7
7
20
0
0
7
7
7
0
0
0
0
0
7
% T
% Val:
14
7
0
0
0
7
0
27
14
7
0
7
0
40
7
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _